Day: April 27, 2018

literature review
CPP/Bioportide technologies have the capcity to reach intracellular sites that may be intractable targets for conventional drugs. Moreover, it is likely that many bioportides achieve a biological influence by a dominant-negative action upon protein-proitein interactions (PPIs).
Your next task is to choose a protein or a PPI interface that might be a useful target for therapeutic manipulation. There are of course many possibilities and I am keen for you to choose your own! Now imgaine you are tasked by a pharmaceutical company to develop a strategy, employing CPPs/Bioportides, to manipulate that intracellular target. You will need to produde a report to pass on to the peptide synthesis team highlighting sequences of peptides that can be screened as potential therapeutics. These might be inert CPPs attached to a bioactive peptide seuquence or a bioportide that is predicted to be both cell penetrant and bioactive. Your project write-up is essentially that report. The results section will contain the sequences and stratagies that you design to influence the activity of your intracellular protein or process. Theoretically, I could pass on your project to next year’s students and ask them to manufacture the peptides you design.

For those of you who decide to embark upon the DRY Project, your literature review should focus on Cell Penetrating Peptides, Bioportides and Protein-Protein Interactions

Paper Topic

Marjorie Shostak’s ethnography, Nisa: The Life and Words of a !Kung Woman, is guided by the narrative of the stories of Nisa’s life. About her stories, Nisa tells Shostak, “I’ll tell you another one now. I’ll break open the story and tell you what is there. Then, like the others that have fallen out onto the sand, I will finish with it, and the wind will take it away.” (36)

In this course, we learn about the stories of many people of many different cultures. At first glance, some of their stories may seem completely different from the events of our own lives. Upon closer examination, we can find many themes that run through the lives of the !Kung also run through our own.

Another major theme of our course is cultural adaptation. From your new anthropologist’s perspective, you should be able to examine a cultural practice in an objective way. For example, does the !Kung practice of sharing meat hurt or enhance their survival as a group? Does it support their health or well-being? A practice can be evaluated in this way even if it is not part of our own cultural norms.

PAPER TOPIC

Compare and contrast the aspects of !Kung life with your own. Choose at least three aspects to discuss. These may be rites of passage (such as birth, marriage, divorce, death) or other aspects of !Kung life (choosing a partner, healing the sick, securing food for consumption), etc.

For each aspect, first describe the practice in !Kung life. (You may rely solely on the Shostak text for this section, or use one of the required outside scholarly sources.)

Second, compare and/or contrast it with the practice in your own culture. Note the similarities or differences. (You may bring in outside scholarly sources in this section.)

Third, evaluate the practice based on its adaptability for the !Kung. Do you think the way the !Kung behave in this situation is adaptive for their health and well-being (even if it is unlike the way we behave in this situation)? Does it aid their success as a group? Give your opinion (analysis) based on evidence from the text or from scholarly sources.

PAPER REQUIREMENTS

Your paper must be 4-5 pages long, double-spaced with 0.8” to 1.0” margins with 10 or 12 point traditional font. The minimum length is 4 full pages. Please provide a References page at the end of the document using APA formatting.

Two scholarly sources are required for this assignment beyond the Shostak text. Scholarly sources come from academic journals or books from a university press. You will need to use the library’s databases (such as ProQuest) or physically check out books from the library to meet this requirement. Please see the TIPS FOR FINDING SCHOLARLY SOURCES handout in the Assignments section of the course.

Please use citations (or quotes) to support your arguments. To cite passages from a text, put quotation marks around a passage followed immediately by the author’s last name and page number in parentheses. Quotes should be brief, under four lines.

For example:

“My heart was so happy I moved around like a little dog, wagging my tail and running around. Really! I was so happy, I shouted out what I saw: ‘The rainy season has come today! Yea! Yea!'”(Shostak: 89)

If you must use a longer quote than four lines, eliminate the quotation marks, single space, and indent the entire quote several tabs from the left margin.

Be sure to explain why you are using a particular quote. A quote by itself does not prove a point. It only provides evidence for your argument. You must make an argument preceding or following the quote.

Using other people’s words constitutes plagiarism. Provide quotes and a reference including the author’s name, title and page number for more than three words in a row that are not your own. Please use APA formatting to provide a reference for the Nisa text and any other texts that you may have used at the end of the document.

Please spell-check your paper (check for typos, mistakes, etc.), organize it into indented paragraphs, and write in a clear and simple style.

You are to assume the role of chief executive of a Destination Management Company of your choice. You are to produce a pre-feasibility study of a new build convention centre for your chosen destination. Your pre-feasibility study would form part of a bid to potential funding partners, in which you are to make appropriate recommendations around the existing events environment, economic situation, funding and operational issues for your proposal.

In addition, students will be awarded additional credit where:
– Students consider the macro environment in which Convention Centres operate.
– Students consider the key stakeholders for the proposal with strategic partners where appropriate
– The overall rationale for the project with specific aims and objectives for the Convention Centre are given
– An appreciation of the economic, political and social implications on the host region is evident
– Consideration is given to the financial viability of the project
– Operational decision making is considered to include project management approaches, and human resources implications
– An appreciation of underpinning research is made evident

1.Critically assess the dynamic nature of the Global Meetings and Events Environment.
3. Critically analyse the economic considerations and funding for large scale events projects.
4. Critically assess the operational management requirements for large scale event projects.

School of Social, Historical and Political Studies
QAA Subject Benchmark for Criminology (2014), SENDA, RRHA, FHEQ
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This module examines concepts and theories of serious and organised crime and evaluates its development, impact and initiatives taken to tackle it. Case study material will include drug smuggling, human trafficking, environmental crime and maritime piracy.
The writer needs to show exceptional level of analysis, showing deep critical engagement with a comprehensive range of contextual material. Demonstration of independent thought resulting in highly original or creative responses to the assignment. Provision of clear evidence of understanding of current scholarship and research based on an extensive range of relevant sources. Extreme clarity of structure demonstrating complete focus of analysis. No obvious errors in referencing or grammar or syntax as appropriate. The writer needs to ensure that all the Learning Outcome are met in this critical analysis coursework. Learning Outcomes are on the coursework brief attached. You are to use the resources below and provide your own. If you can use Journal articles that’s a bonus.
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1.)The writer needs to be knowledgeable that holds a Masters or PHD in Law and is able to critically analyse.
2) The writer needs to make sure that Learning Outcomes (LO), LO1,LO2,LO3 are covered in this critical analysis coursework. Marking Grid that you should follow. 90/100% Exceptional level of analysis, showing deep critical engagement with a comprehensive range of contextual material. Demonstration of independent thought resulting in highly original or creative responses to the assignment. Provision of clear evidence of understanding of current scholarship and research based on an extensive range of relevant sources. Extreme clarity of structure demonstrating complete focus of argument. No obvious errors in referencing or grammar or syntax as appropriate
3) The writer needs to Choose 2 examples of transnational organised crime that have an impact on people in Britain and analyse their causes and consequences.
4) The writer would need to use data, tables, graphs and charts as part of his critical analysis for both chosen areas for crimes in the UK.
5) I need to achieve 90/100% in this coursework, I would like you to follow the marking grid to ensure that you are meeting the first class grade. All the additional information is uploaded including the critical analysis coursework. 6) I would like you to communicate with me throughout the process of this coursework, I would like updates regularly. 7) I have uploaded the Coursework brief, Harvard Referencing Guide, Task words, Guide to planning your assignment, reading list for my coursework this should help you to find resources to my coursework question, also presentation slides on my lectures etc make use of this. Just make sure it’s consistent, readable, organised and no complicated big words. 8) I would like you to use your own resources and research, to answer the coursework question. 9) If you don’t understand anything don’t assume just ask

School of Social, Historical and Political Studies
QAA Subject Benchmark for Criminology (2014), SENDA, RRHA, FHEQ
_________________________________________________
This module examines concepts and theories of serious and organised crime and evaluates its development, impact and initiatives taken to tackle it. Case study material will include drug smuggling, human trafficking, environmental crime and maritime piracy.
The writer needs to show exceptional level of analysis, showing deep critical engagement with a comprehensive range of contextual material. Demonstration of independent thought resulting in highly original or creative responses to the assignment. Provision of clear evidence of understanding of current scholarship and research based on an extensive range of relevant sources. Extreme clarity of structure demonstrating complete focus of analysis. No obvious errors in referencing or grammar or syntax as appropriate. The writer needs to ensure that all the Learning Outcome are met in this critical analysis coursework. Learning Outcomes are on the coursework brief attached. You are to use the resources below and provide your own. If you can use Journal articles that’s a bonus.
————————————————————————
1.)The writer needs to be knowledgeable that holds a Masters or PHD in Law and is able to critically analyse.
2) The writer needs to make sure that Learning Outcomes (LO), LO1,LO2,LO3 are covered in this critical analysis coursework. Marking Grid that you should follow. 90/100% Exceptional level of analysis, showing deep critical engagement with a comprehensive range of contextual material. Demonstration of independent thought resulting in highly original or creative responses to the assignment. Provision of clear evidence of understanding of current scholarship and research based on an extensive range of relevant sources. Extreme clarity of structure demonstrating complete focus of argument. No obvious errors in referencing or grammar or syntax as appropriate
3) The writer needs to Choose 2 examples of transnational organised crime that have an impact on people in Britain and analyse their causes and consequences.
4) The writer would need to use data, tables, graphs and charts as part of his critical analysis for both chosen areas for crimes in the UK.
5) I need to achieve 90/100% in this coursework, I would like you to follow the marking grid to ensure that you are meeting the first class grade. All the additional information is uploaded including the critical analysis coursework. 6) I would like you to communicate with me throughout the process of this coursework, I would like updates regularly. 7) I have uploaded the Coursework brief, Harvard Referencing Guide, Task words, Guide to planning your assignment, reading list for my coursework this should help you to find resources to my coursework question, also presentation slides on my lectures etc make use of this. Just make sure it’s consistent, readable, organised and no complicated big words. 8) I would like you to use your own resources and research, to answer the coursework question. 9) If you don’t understand anything don’t assume just ask

Assignment Task: Essay

“Actor Network theory is a suitable theory for describing how humans and technology connect” Discuss this statement by following the tasks below.

Select TWO computing news stories of your choice, published anytime between 01/09/2016 and 30/12/2016. Analyse these using Actor Network Theory.

Your analysis should be written as an essay, and include the following points:

• A definition of Actor Network Theory including the key terms actant, assemblage and network

? Name and categorise the main actants in your stories. Describe how they are connecting to and “acting” upon other actants in the assemblage. Include the connection between the hardware and software actants, as well as other types of actants.

? Describe how the actions of the software actants can enhance management functions for both computing news stories.

? Discuss some of advantages/disadvantages of the constant use of both computing and the internet in modern society. To do this, compare and contrast the viewpoints of a range of theorists and critics explored throughout the module.

? Conclude by summarising how your answers relate to the statement “Actor Network theory is a suitable theory for describing how humans and technology connect”.

? Add an appendix which includes definitions of at least four computing terms or concepts used in your assignment. One of these terms MUST be software.

Deliverables

Your content will follow the structure outlined on page 3.

Task 1 is worth 100% of the total marks for the module. The marking criteria is outlined on pages below.
Suggested essay structure

Cover Page
Assignment title, module code, student name, student number and submission date.

Table of Contents

A list of headings and page numbers.

Introduction
How will you introduce your essay?
Tell your reader the aim of this assignment and how you intend to go about discussing or proving this aim. What else will you be telling your reader. No definitions here. Just describe in very general terms what you will be doing.

Main Body
Define Actor Network Theory
What type of theory is it? Who developed it? What does the term actant mean? What does the term assemblage mean? Here you will need to include in-text citations with your references properly laid out in your references section. The format you must follow is Harvard Referencing format.

Apply Actor Network Theory to Computing Story 1
Don’t retell your story. State your story in one or two sentences with in-text citations. Include the news story in your references section using correct Harvard Referencing format. You must apply Actor Network Theory to your story now. This means that you are describing the connections between actants and what happens as a result of these connections. To do this identify your actants, and categorise their scale, i.e. digital, software, hardware, human, cultural, structural and describe and analyse how some of these actants are acting on each other (the push/pull of actants – when an actant ‘acts’ on another actant, how does this change/modify the behaviour of the actant being ‘acted upon’)  How does this affect the network of actants? Are the actants both human and non-human?

State how management (the coordinated efforts of humans/technology in order to achieve goals efficiently) has been enhanced in the story by the software. This could be management of self or management of an uprising or management of the business etc.

Apply Actor Network Theory to Computing Story 2
Don’t retell your story. State your story in one or two sentences with in-text citations. Include the news story in your references section using correct Harvard Referencing format. You must apply Actor Network Theory to your story now. This means that you are describing the connections between actants and what happens as a result of these connections. To do this identify your actants, and categorise their scale, i.e. digital, software, hardware, human, cultural, structural and describe and analyse how some of these actants are acting on each other (the push/pull of actants – when an actant ‘acts’ on another actant, how does this change/modify the behaviour of the actant being ‘acted upon’)  How does this affect the network of actants? Are the actants both human and non-human?

State how management (the coordinated efforts of humans/technology in order to achieve goals efficiently) has been enhanced in the story by the software. This could be management of self or management of an uprising or management of the business etc.

Contemporary Debate
What are the theorists saying about computing in general?
Discuss both sides of the argument from both a techno-optimistic and techno-pessimistic point of view. Use key terms from the course to add value here.

Limitations of Knowledge
Do we really know the long term effect of computing? Is ANT a perfect theory? What problems did you encounter with it?

Conclusion
What did you learn? Did you prove the assignment task. Summarise your findings. No new knowledge here. Link your conclusions or recommendations back to your title.

References
Citations are listed in alphabetical order by the author’s surname (last name).

Appendix
Include four definitions of key terms from this module. One of these MUST be software. The other three can be any three terms of your choice.

Further notes on the appendix for your guide: In your essay, you may have referred to an image or chart. Let’s say that in the main body, you have written something like “Appendix A shows that there are many actants connected in order to achieve the aims of the assemblage. This essay will focus on just a few of those actants” Now in your Appendix section, you include the image that you have drawn. Give it the title, for example, “Appendix A: A mind map showing how the actants are connected in the assemblage”
If you did not create the image/chart yourself, you will need to put a citation under the image/chart and include the original source in your references section.

N.B. For good academic practice, please ensure that the same font of the same size and colour is used throughout your essay, and that your document has the same line spacing throughout.

Assessment Criteria

Explanatory comments on the assessment criteria
Maximum marks for each section
Knowledge & Understanding

Clear definition of Actor Network Theory
Two relevant news stories outlined
Clear explanation provided of how management is enhanced by the software
Well written appendix with clear definitions of required terms

45
Intellectual & Cognitive Skills

Actor Network Theory well applied and connections between actants discussed
Contemporary debate uses relevant arguments from the techno-optimists and techno-pessimists to provide a balanced and well-formed argument that demonstrates understanding of how contemporary computing fits into the knowledge economy.
Correct use of key terms from the module

30
Graduate Skills

Demonstrates an understanding of limitations of knowledge
Essay format
Use of business English Use of Harvard referencing

25

Total
100
Learning outcomes
• Collect, analyse, present and comment upon business
to be examined in
data.
this assessment

• Identify the relationship between computer hardware

and software.

• Describe the most common types of software

programmes and explain how they may be used to

enhance management functions.

Choose two of the UK’S largest supermarket chains companies from the list provided (Tesco, Sainsbury’s and Morrisons) and download the companies’ annual reports from their website. Produce the 2013, 2014 and 2015 ratio table for the companies you have chosen from the list above (Profitability, Liquidity and Efficiency ratios as performed in class.) Choose two ratios from each category. Based on these ratios and any other additional information available from the annual reports, compile a report comparing the performance of the companies selected.

Learning outcomes to be examined in this assessment :
• Describe and analyse the role of accounting information in a business context.
• Analyse a set of financial statements including balance sheet, profit and loss accounts and cash flow statements.
• Demonstrate the relationship between accounting data and financial planning and resource allocation decisions.

Please write up your comments in no more than 2500 words (Times New Roman, 11 font, single spaced).
Demonstrate the ability to relate theory to the real world.

Problem – Pharmacy

You are the IT Director at a 175 acute care bed hospital in central Illinois that has been using Meditech for its core health care IT financial and admitting/registration applications. The organization has just completed the development of a strategic IT plan that calls for the implementation of a number of clinical applications during the next 2-3 years. The Director of Pharmacy has stated she would like to be among the first to begin implementing an automated clinical solution in her department. She has been pushing Bridge Medical as her system of choice and is trying to get other clinical department directors to agree upon Cerner as their system of choice. She is taking this position because she believes Bridge Medical will satisfy the demands of the “five rights” for medication safety while Meditech doesn’t have the capabilities she needs to be successful in this area.

The CFO of the hospital (your boss) recognizes if the hospital purchases the Bridge Medical clinical application then there could be data integration and billing issues from using two different IT suppliers. On the other hand, if the CFO dictates integration from a single supplier, then the clinical department directors could be very upset. The CFO has asked for your opinion on this matter. Should the hospital consider the purchase of Bridge Medical’s clinical application or should the hospital consider Meditech as its clinical system of choice?

He is asking that you prepare a 15-20-minute presentation that he’ll present to the hospital’s executive committee stating the background of the situation, an understanding of the problem, your position with supporting data and references, and your recommendation(s).

For this assessment you produce a document presented using digital or multi-media. This document should be an infographic which visually documents the content as per the assignment guideline below. You can produce a short video or an A1 sized infographic sheet.

The infographic will highlight the ‘Emergence of new economies and the decline within Europe: using examples of BRIC, MINT, PIIGS, BREXIT.

Graphics, images, statistics, tables etc. should all be used to engage the reader and show how the trading economies of the world have changed. The decline of the EU and the rise of economies in India, China, Brazil etc. Brief explanations should be provided either in text or diagrammatic format.
Overall the key learning outcomes assessed include:

13. Demonstrate a clear ability to source information and to present this using correct acknowledgements and referencing of all sources

P1 Carry out research into issues relevant to trends in globalisation.
T1 Communicate effectively using a variety of media and formats
T2 Apply a range of Information technology skills when researching and presenting information

?Write a 10 page with out the appendix , double spaced paper addressing your case study. Charts and graphs should be placed in an Appendix and are not part of your page count.

? Write your paper from the perspective of a consultant who has been hired by the company to provide recommendations to solve the problem(s) laid out in the case study.

? As part of this paper, you must apply multiple concepts that have been covered during this class and apply them to your chosen case study.
So for example, a recommendation based on supply chain management would be appropriate for the paper; a recommendation based on a new marketing plan would not.

? Use Times New Roman, 12-point font.

Identification of Operations Issues (20%)
Identify operations issues that we have discussed during the course of the semester that the company in your case is facing.
Analysis and Evaluation of OM Issues (30%)
Discuss how the identified issues are affecting the company and what options the company has to address the issues from an operations perspective.
Recommendations – Application of theory & analysis and utilizing OM Strategies (40%)
Provide clear and actionable recommendations for how the company should address the issues facing them. These recommendations should be based in Operation Management strategies that we have discussed during the course of the semester.
Form and Presentation (10%)
Your paper should be organized in a clear and professional manner.

The reference is:
Heizer, Render. (2013). Operations Management. Prentice Hall. 11th edition