Throughout this course you will be learning how our genes shape what we look like, how they influence behaviors and how mutations can cause diseases. But is this all we are? Lets consider a complex issue to get things rolling: smoking. We all have nicotinic acetylcholine receptors in our brains. These receptors, located on our neurons (cells in the nervous system) bind the naturally-released neurotransmitter, acetylcholine. They also bind, as the name implies, the drug nicotine. Variants of a gene called CYP2A6 are associated with the speed at which a person metabolizes nicotine. A fast-metabolizer smokes more. Can we predict which individuals might respond to specific smoking cessation medications using this information? How can we test this? Is it only our genes that mandate the addiction? Can we just blame our genes? Is it ethical to offer only some individuals medication? For this discussion, you will read some articles and begin to analyze the data supporting evidence for the gene and behavior. Try not to use personal experience, but instead approach this subject as an objective scientist gathering and critiquing the data.

Since we cannot always use human subjects, for ethical reasons, to study genes and behavior, animal models often give us a close look into cellular and molecular mechanisms. Think about all the similarities between humans and other organisms, not just the differences. For example, fruit flies have brains, eyes and muscles. They walk, mate, eat, and sleep. Both organisms are made of cells, organs and organ systems. Certainly there are similar genes and proteins that drive their development and behaviors. Nevertheless, we are not exactly the same. Keep this in mind as you participate in discussions and as you proceed throughout the course.

Read the following articles:

Tyndale RF & Sellers EM (2001). Variable CYP2A6-mediated nicotine metabolism alters smoking behavior and risk (Links to an external site.). Drug Metab Dispos.
Quaak, et al. (2009). Genetic variation as a predictor of smoking cessation success (Links to an external site.). A promising preventive and intervention tool for chronic respiratory diseases? Eur Respir J 2009; 33: 468480.

References
http://dmd.aspetjournals.org/content/29/4/548

https://erj.ersjournals.com/content/33/3/468

1. How did their childhoods affect the lives of John Wayne Gacy and Ted Bundy?

2. Why did Ted Bundy pick the type of victims he did?

3. Why did John Wayne Gacy pick the type of victims he did?

4. A psychopath acts out of rage and impulse.  A sociopath plans their crimes.  A psychopath may feel guilty after their crimes.  A sociopath feels no guilt at all for what they did.  Are John Wayne Gacy and Ted Bundy psychopaths or sociopaths?  FULLY explain your answer.

5. Why were Gacy and Bundy able to escape capture for so long?  Would murderous sprees such as they committed be possible today with todays technology?

Week 1 Discussion Board
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Watch: American Public Health Association: “Healthiest Nation in One Generation”and think about a typical day in your life. Identify the ways that public health affects it. Interact and discuss with your classmates how public health affects different aspects of each of your lives.

Watch Video
Healthiest Nation in One Generation
https://youtu.be/DuBggj7Zd3A

What is Public Health
What is Public Health?? (https://youtu.be/t_eWESXTnic)
What is Public Health??

You are asked to complete 4 Jupyter notebooks which are provided with these guidelines:
a3 1.ipynb
a3 2.ipynb
a3 3.ipynb
a3 4.ipynb
A separate notebook has been provided for each question since the questions are independent of each other and so that the notebooks load and run faster. The questions are based on activities that you have already completedinlabs,mainlyduringweeks8-11ofthemodule(althoughearlier material may also be relevant). Any code you have developed during the labs can be submitted as part of your answers to the questions in the assignment. To score highly on this assignment you will need to demonstrate that you:
understand the theory and your code;
can write and document high quality python code;
can develop code further to solve related problems;
can carry out experiments and display results in a coherent way;
can analyse and interpret results; and can draw conclusions and understand limitations of the technology.
can design and build prototype systems combining off-the-shelf technologies into a practical language processing system
For this report you should submit 4 Jupyter notebooks containing all of your answers to all of the questions (or 3 Jupyter notebooks for questions 1-3 and a pdf document for question 4). You may import from standard libraries and the sussex nltk resources which you have been provided with. If you wish to import any other code, it must be included in the zip le with your Jupyter notebooks. It must be possible for the assessors to run your Jupyter notebooks.

Your should submit either a “Word” document that lists your responses to the questions listed below.  You must provide both a written explanation and the relevant screen capture(s) that provide support for your explanation. List your responses according to the outline presented below:

Reduce inventory of slow-moving and obsolete products
How do the sales of each product compare with forecasts?
How do the sales of each product compare with prior year sales?
How are the sales of each product compared with the competition?
How are the sales of each product compared with other product sales?
If there is a particular product not selling well, is this specific to any particular region?
Enhance the marketing strategy by product type
Are there any poorly performing products in high-performing countries?
If there is a poorly performing product in a high-performing country, how is this product performing compared with the sales in other countries and the competition?

 

The purpose of this discussion it to help you learn to discern credible and not credible sources of information on the Internet and elsewhere.

Go to a search engine and find one credible and one not credible source on the Internet. You can use Yahoo or Bing. You can also use UMUC library.  Once you find both sites then evaluate each per the UMUC criteria, which are at the web sites below. Post your evaluations.

Once you have post you Week 1 Initial Discussion posting then go and investigate the web sites that your classmates have found. What are your thought on their web sites? You need to reply to two of your classmates.

Prior to starting this discussion topic, read the information below.

Locating Reliable Nutrition Information on the Internet *

The purpose of the discussion is not teaching Internet searching skills, but to show the mind-boggling amount of information that is out there, also to see if you can find some reliable sources of nutrition information on the Internet and to help you learn to evaluate the information that is out there. Upon completion of this assignment you will be to evaluate and identify a reliable nutrition web sites on the Internet.

Before you go any further, go the UMUC site on Evaluating Web sites at: http://sites.umuc.edu/library/libhow/websiteevaluation_tutorial.cfm

 Evaluating Sources at https://www.umuc.edu/current-students/learning-resources/writing-center/writing-resources/evaluating-sources.cfm

Extra resources from the University of California Santa Cruz

http://library.ucsc.edu/help/research/evaluate-the-quality-and-credibility-of-your-sources

Read this and print it out to use when you evaluate the web site that you find.

Amino acids are the building blocks of protein. We will discuss when we discuss proteins and amino acids. Unless you must follow a very specialized diet you can obtain them from food. You do not need to buy amino acid supplements. In fact it is not recommended to buy and/or consume amino acid supplements.

Now go a search engine Yahoo.com http://yahoo.com “amino acids” or Bing https://www.bing.com/ . What sites do you find?  Please list the URL so that your classmate and I can go to the web site. Are any of these web sites not reliable Evaluate it according to the five UMUC evaluate criteria.

To see reliable source of information go to the  University of Maryland University Colleges  Library Resources  page. https://sites.umuc.edu/library/libresources/

Once you get to the Library Resources  page click on click on Research Guides ( it is under Articles). This will take you to the Research Guides page.

On the Research Guides page  click on Heath and Medicine.

Once you get to the Research Guide for Health and Medicine: Resources page

 Under  Recommended Databases for Health and Medicine, click on Health Source : Consumer Edition.

Once you get there do a search on amino acids. Do not include the quotation marks.

What site did you find? Please provide the URL so that your classmates and I can go to the site. Evaluate the site according to the UMUC evaluation criteria.   

Now compare your two sites according to the UMUC criteria. Please post your evaluation to the conference room

Note: Do not be alarmed at the depth of the articles that you will find at places like PubMed.  You  may just be starting your University career therefore may not have taken many or any biology and chemistry classes.  Having a background will help you to understand these articles.

Note: This topic has its own set of rubrics.

 You may also want to check out the following link https://sites.umuc.edu/library/libhow/articles.cfmAt that link you will find a link to “Finding Articles: Finding and Evaluating Scholarly Articles”.

 During Week 1, the Nutrition Navigating Discussion will be available. Please post your two evaluation there. You will also need to reply to the initial post of two of your classmates.

You must start a thread before you can read and reply to other threads 

Choose a high-profile, contemporary American criminal case (Aaron Hernandez case)to review. In a 57 page paper (12501750 words), prepare a case write-up that incorporates all aspects of the criminal justice systemfrom police investigation, to arrest, evidence, court proceedings, and eventually sentencing.

Describe the nature of the case, citing it in appropriate legal format (i.e., Miranda v. Arizona, 1966).
Explain the investigation. What legal foundations and constitutional laws and amendments were present? What type of defense, if any, was used?
Describe the court proceedings; pre-trial hearings, indictments, the trial, defense and prosecution arguments, and court outcomeacquittal, guilty, not guilty, NGRI, GBMI, etc.
Finally, describe the correctional phase, if applicable: jail, prison, probation, parole, etc.
Would there be a significant difference if adjudicated in another level of court (i.e, federal)? Would the punishment be more, or less severe? Would the evidence be handled differently?
Summarize the case and offer your analysis of the proceedings. What are your thoughts about the investigation, evidence, court proceedings, and verdict? Make sure you support your conclusions with cited and referenced materials.

For this assignment, you are to watch the film, The Good Lie, and answer the following questions in complete sentences (essay format):

(1) While watching the movie, document five scenes that discuss or provide insight into family studies. For each of the five scenes that you document, write a brief explanation about why you chose the scene.
(2) How does the movie depict family life in Sudan? What are some of the challenges families face? Explain in two paragraphs.
(3) What is the moral of the story? Does this movie serve as an effective social commentary on war-torn, impoverished countries? Why or why not? Explain in two paragraphs.

Use SPECIFIC EVIDENCE from the film to support your answers.

A note on the course concepts will be attached.

The writing style and tone of language for this assignment should be sophisticated and adhere to university-level writing. If you have any questions or concerns, please let me know, and I will respond to you as soon as possible.

Begin thinking about a topic and audience for your Teaching Project assignment. The submission of the topic and audience are due week 2. Submit your health topic and the expected audience (peers/patients/community group) and consider the age range of participants. For example: if your topic is “Crutch walking for the Hip Replacement patient,” focus on the 50- 90 aged participant. You will need to consider age-specific considerations when developing your lesson.

Teaching Project Assignment (due week 6):

The Teaching Project is an individual project.  Each of you will identify either patients, peers, or a community group on which to focus. Your topic and audience must be approved by me no later than by week 2.  Incorporate content that is reflective of learning principles and cultural influences that impact learning supported by current professional sources. The teaching project is worth 30% of the course grade.The entire project consists of 2 parts: The Lesson Plan (template fully completed) & the Reflective Narrative. The following must be included in the lesson plan:

Goal of the teaching session
Measurable behavioral objectives containing all components (ABCD Method)
Content outline
Reasonable time frames (identify contextual factors related to time frames: privacy, space, interruptions, time, culture, limits, etc.)
Resources used
Methods of teaching
Tools for teaching
Evaluation of learning methods
Please make sure that there is continuity of all components.

Attach a reflective narrative (MS Word document) that documents your attention to adult learning principles, cultural factors, and contextual factors.

References other than your text are expected. You are expected to use citations within the body of your narrative document as well as the lesson plan.

A separate reference page that includes all references used within the project must be included.

The narrative and references are to be in APA format (Links to an external site.).       

Use the following resources to help guide you:

Teaching Project Assignment Guidelines.doc Preview the document
Teaching Project RubricPreview the document
Lesson Plan Blank.docPreview the document
lesson plan reference sample.doc
Developing Teaching Plans.ppt Preview the document           

Please submit a proposed teaching topic and audience by Wednesday at 11:59PM via this assignment link in a MS Word document. The topic and audience must be approved prior to the development of your 3 behavioral objectives which are due this week by Sunday at 11:59PM. Therefore, it is imperative that your topic and audience are submitted in a timely manner, so please plan appropriately.

Research one other major criminal justice system. In your initial post, compare and contrast the system to the American criminal justice system from the following perspectives: the way law enforcement personnel handle an investigation, the way a suspect is treatedincluding their civil rights and liberties, if anythe way their court system handles the case, and the potential outcomes of those cases.
Your initial post must be at least 200250 words, with citations and references