In recent decades, there have been a range of conspiracy theories about her death, most of the theories contended that she was murdered by John and/or Robert Kennedy, who she allegedly had love affairs with. These theories claimed that the Kennedys killed her or had her killed because they were worried that she would make their love affairs and other government secrets she had public.
Day: October 22, 2020
Question 2:
is related to ADME pharmacology subject
in part A I need 3 metabolic pathways of the molecule in the question. and what are the enzymes family of each pathway with a draw of the possible product. 3 small paragraphs are needed in this part.
some notes in this part:
I have found 2 metabolic pathways
Aromatic oxidation adding [OH] in the aromatic ring. the enzyme family is cytochrome p450
Dehalogenation is removal of chiorine in aromatic ring the enzyme family is cytochrome p450
part B:
Definitions of Biopharmaceutics Classification System (BCS) and Lipinskis rule of 5
which class of the drug molecule belongs to and explain why?
notes:
in the drug there are lipophilic groups that can permeate the membrane and is not soluble in aqueous mediums. therefore, the drug classification is class II drug with high permeability and low solubility.
part C:
in this part I need discussion on how to make class II drug has a high bioavailability percentage and why. what kind of mechanism should be used. and formulation strategies.
notes:
it needs solubility enhancement to increase the solubility and bioavailability and make it a class I drug. (micelle formation, particle size reduction, addition of co-solvents).
Lipophilic molecules it will face difficulties passing from the intestinal lumen to the enterocyte.
pancreatic lipase and the co lipase will digest the triglycerides (complex lipids) make it fatty acids and monoglycerides which leads to particle size reduction.
monomers will bind with phosphollpids, amphiphilic molecules and bile salts to form mixed micelles to help transport the drug molecule to enterocyte membrane.
the enterocyte the drug molecule will bind with chylomicrons (large lipoproteins formed via core expansion) and travels into the lymph instead of the blood stream.
Other mechanism to increase the solubility and bloavailability of lipophilic drugs turning them from class Il to class I drugs.
reference is needed
the words limit is 750
Question 4:
is related to biology and psychology subject
in this question you need to write a concise article related to FMT therapy:
Causes of CDI and its impact on patients; recommended first line therapies, the current use of FMT, how it works and efficacy compared to antibiotic therapy.
Key considerations in offering this therapy, focussing on what you consider to be the take home message for UK pharmacists from the Krajicek paper.
only refer to this link https://pubmed.ncbi.nlm.nih.gov/30268564/ Vancouver style only I have attached the pdf file for this question.
the words limit is 400
Question 5:
is related to pharmacology and pharmacy practice subject.
it is divided into 3 parts
part A:
what is dietary non-starch polysaccharides?
notes:
complex carbohydrates other than starch and classified as fibres it is mostly component of plant cell walls that cannot be digested. they soluble and insoluble fibres and can be found in fruits, vegetables and wholegrains.
some references are needed
part B:
the recommended daily intake for NSPs in the diet, in the UK?
in the UK, 30g per day for adult.
reference is needed
part C:
the role of NSPs in the diet, considering why they are a required component of a healthy balanced diet.
in wholegrains there are insoluble fibres good for constipation it attracts water to soften the stool and bulk it up. reduces the transit time through the GIT meaning going to the toilet. soluble fibres found in fruits and vegetables are important because it delays the gastric emptying lead to feel fuller for longer time and the cholesterol reuptake is decreased by binding to bile salts.
reference is needed
the words limit is 200.
References should be in Vancouver style only.
A final assignment is due by midnight after Graduate Mini-1 Exam Days (by October 23, Friday, 11:59 pm). The essay consists of the analysis of a case study, making use of the tools and materials discussed in class. The paper should not exceed 1,500 words. The exercise will be open-book and open-note. You will submit your essays via CANVAS. [Writing: 5; Theoretical Accuracy: 5; Logical reasoning: 5; Engagement with possible objections to your argument: 5] Late assignments will be penalized by negative 5 points for each calendar day they are late unless otherwise noted. No exceptions.
Final Essay Case: David Bolllier, Stephanie Weiss, and Kirk O. Hansen, Merck & Co., Inc. (A)Preview the document 9-991-021, The Business Enterprise Trust. (The case from Class 11).
Instruction 1:You are CEO in the case. Everything is the same as described in the case, but the year. It is 2020. Would you develop the medicine, Ivermctine, for the third world? Yes or No. Choose one and defend it.
Instruction 2: You are going to write a letter to investors (e.g., BlackRock, etc.) to explain your choice. So the writing must be accessible to them. If you want to use for instance the generalization principle, you must explain it in an intelligible manner to them. Just saying that” x, y, z, so it does not pass the test,” is not itself persuasive to them. You should explain why the test is ethically important to them. The same challenge applies to all other tests, too, if you opt to use any of them.
Instruction 3: The letter must finish with a general statement about “What is business for?”
Do not write responses in essay form. Write separately
This week, you will be discussing three readings:
Reading 1:
Reading 1: Virginia Woolf Professions for Women
“Professions for Women” was first delivered as a speech in 1931 at the Women’s Service League. Later on, it was included as an essay in the collection of The Death of the Moth and Other Essays. She makes many points in this speech/essay. Obviously, she talks about the professions for women. She begins by talking about her field, which is literature and she points out that she was not the first one to be a woman writer. She points out to important women writers such as Fanny Burney, Jane Austen, George Elliot and others who happen to be prominent writers who paved the way for Virginia Woolf as a woman writer.
She talks about the kinds of obstacles or challenges that she faces to become a writer; she names the challenge as the struggle with the phantom: very few material obstacles in my way” such as the phantom that represents the force that represses women. Woolf calls for fighting the image of the repressed and submissive Victorian image of the woman: “Killing the Angel in the House was part of the occupation of a woman writer.” When she fights this phantom, which she calls the Angel in the house, she would be liberated. The question Woolf asks as she wonders about writing is about how can a woman write and express her thoughts if she does not have her independent self and does not formulate her own thoughts and thinks as a woman and not as a man in a patriarchal; society. Woolf deals with two major crises, as she talks about in her speech/essay. Does she overcome them? Read the essay and answer the question
Read about the Victorian image and the Angel in the House concept: http://academic.brooklyn.cuny.edu/english/melani/novel_19c/thackeray/angel.html
1- Does Virginia Woolf overcome the two crises/obstacles she talks about in her essay? Explain. Read the essay and answer the question
2- Does your reading of Woolf’s essay inspire you? Explain
Reading 2: Baldwin’s Notes of a Native Son
Listen to the reading of the story Part I: https://www.youtube.com/watch?v=dMgJl9aMGoU&feature=youtu.be, Part II: https://www.youtube.com/watch?v=z2ca80-vtRA&feature=youtu.be, and Part III: https://www.youtube.com/watch?v=6G37ThmcDGA&feature=youtu.be
3- What does Badwin talk about?
4- What is the major struggle in Baldwin’s “Notes of a Native Son”?
5- What do you find similar/different between Woolf and Baldwin in terms of thematic comparison?
Reading 3:
Stephanie Ericsson. “The Ways We Lie.” P. 157
6-What is the main theme that Ericsson discusses in this article?
Hello there I have a 5 page research paper to do for us history college class. The paper has to answer the following question , Did the New Deal End the Great Depression? Has has to include articles backing up your answer and also a movie/ documentary in there if possible Has to be 5 pages long including MLA format citation.
Thank you very much !
the information that you will use to meet your example requirements. This support provides the information to back up point(s) you are trying to make. The support you will use will come from all of these resources:
Three Outside Sources
Up to five quotes. Quotes may not be more than two lines.
No block quotes or illustrations
DB #4: Accounting Software:
Accounting software used by healthcare organizations is instrumental in providing financial accounting data and financial information, support compliance, streamline operations creating efficiencies & improve effectiveness, and guide the growth & competitiveness in the marketplace.
In this discussion, in no less than 200 words
Please describe accounting software that the healthcare industry uses (in the large integrated delivery systems, hospital systems, health plans, pharmaceutical companies, managed care entities, medical groups, and physician offices).
Compare the features that support the management of accounting and financial operations, as well as the healthcare business.
In addition, please reply to one of your classmates posting in no less than 100 words.
Both postings should present quality, thoughtfulness, and unique perspectives.
Here I copy & paste one of my classmate’s (Ashima) post, you should reply her post for 100 words:
Healthcare accounting software is a system that manages a healthcare practices revenue cycle. Its purpose is threefold: automating the billing process to relieve the clerical workload on the staff, streamlining the process by collecting all the necessary steps in a single interface, and serving as a secondary net for catching errors that can be costly to both patients and practices.
Healthcare accounting software streamlines patient management tasks like patient accounts, collections and copays. Additionally, it handles back-office and billing functions such as accounts payable, accounts receivable and general ledger features. It also helps manage the often complex workflow of processing claims with insurance providers and Medicare/Medicaid programs and automates the process of importing data, checking it for accuracy (scrubbing) and generating reports based on the data for decision-makers to utilize.
Finally, a good healthcare accounting system tracks billing information, giving a complete record for each patient that offers an overview of billing history, their payment habits, level and type of insurance coverage, etc. This record lets the healthcare firm send bills, request payments, send automated reminders and deliver collections letters if necessary (Adair, 2019).
The range of choice healthcare firms have when it comes to accounting software is astounding; however, most leaders in the business today also integrate Enterprise Resource Planning (ERP) systems within the accounting software. ERP systems are business management tools that give users an integrated view of core business operations, such as cash flow, production capacity, orders and purchasing, and payroll. The systems gather and consolidate data from across several departments to facilitate information exchange and automate back-office functions. In healthcare, ERP eliminates financial data siloes that have traditionally separated back office functions. With an ERP system, providers can manage supply chains with greater ease and break down the walls between front-end revenue cycle management duties, such as patient access, and back-end responsibilities, including claims management (Top 10 Enterprise Resource Planning (ERP) Vendors By Hospital Use, 2019).
Industry leaders in healthcare accounting include Oracles Netsuite (which is used by companies such as Aviva Systems Biology and Invisalign Australia for its great customer relationship management resources, real-time reporting and built-in internal controls) and Sage Intacct (which is used by Vera Whole Health, the Public Health Accreditation Board (PHAB), University Clinical Health, Accurate Neuromonitoring and Tri-County Mental Health Services Inc. for its HIPAA-compliant healthcare cloud accounting software) (NetSuite.com, n.d., Healthcare Accounting Software, 2020).
TERM PAPER
5 pages in length, double spaced, 12 pt font Times New Roman only, 1 margins
_________________________________________________________
Watch the movie Sleepers. Students only need to watch the first part of the movie (approx. 33 min)
This movie shows what happens to four boys who due to extremely poor judgment and reckless behavior become involved with the criminal justice system.
Assume for the purpose of this paper that the charges against the boys are Mischief causing actual danger to life (to the man in the subway entrance), Mischief Over $5,000 (for taking and damaging the hot dog vendors cart), and Theft Under $5000 (for stealing the hotdogs). As well, assume that the boys are 13 and 14 years old at the time of the incident.
Using the movie storyline as a reference point:
Outline how this case could have been dealt with under the restorative justice system and the retributive system of justice.
Provide your opinion/perspective as to which system (restorative or retributive) should the boys be dealt with and why.
Discuss some of the factors presented in the movie that can explain the boys’ criminogenic behavior.
*Make sure you reference your sources with properly cited in-text references and source material with a list of references in APA style. You must use at least 3 scholarly sources other than the text.
*Powerpoint material should not be used as original source material.
*Use of legislative references (i.e. Criminal Code and YCJA) is encouraged
Evaluation: Your essay will be graded using the following criteria:
Quality of your analysis
Structure of your essay (how well you develop a clear, coherent report; introduction, focus statement; body, conclusion)
Direct references to and citation of materials
Problems with organization, logic and clarity, errors in grammar, spelling, and syntax, and not meeting technical requirements will reduce your mark
Your paper must include APA style in-text citations and a complete reference list of all sources used with at least 3 scholarly sources other than the text
Any essay without a bibliography will receive a mark of zero.
Any essay without proper APA style in-text citations will receive a maximum of 50%
All papers must be handed in on the due date. Any papers handed in late (without a valid excuse) will be subject to a reduction in the mark, as per the penalty in accordance with college policy.
This course serves a primer of the Black Experience globally, but primarily focused on the United States. However, Black American cultures, including diasporic Black cultures have had a profound influence on global events and cultures. This includes languages, cuisines, music, religion, etc. Using examples from the course and from your own knowledge, illustrate in a 3 to 5-page essay, the ways that Diasporic Black cultures have influenced non-black cultures either regionally or globally. You can focus on a specific area, nation, or geographic region. You will be evaluated on your understanding of concepts covered in class and in the readings. You are expected to engage with the readings while developing a cogent argument to support your stated position.
want to focus specifically on fashion and music
Assignment : Change Implementation and Management Plan
It is one of the most clich of clichs, but it nevertheless rings true: The only constant is change. As a nursing professional, you are no doubt aware that success in the healthcare field requires the ability to adapt to change, as the pace of change in healthcare may be without rival.
As a professional, you will be called upon to share expertise, inform, educate, and advocate. Your efforts in these areas can help lead others through change. In this Assignment, you will propose a change within your organization and present a comprehensive plan to implement the change you propose.
To Prepare:
Review the Resources and identify one change that you believe is called for in your organization/workplace.
o This may be a change necessary to effectively address one or more of the issues you addressed in the Workplace Environment Assessment you submitted in Module 4. It may also be a change in response to something not addressed in your previous efforts. It may be beneficial to discuss your ideas with your organizational leadership and/or colleagues to help identify and vet these ideas.
Reflect on how you might implement this change and how you might communicate this change to organizational leadership.
Assignment:Change Implementation and Management Plan
Create a narrated PowerPoint presentation of 4 or 5 slides with video that presents a comprehensive plan to implement the change you propose.
Your narrated presentation should be 45 minutes in length.
Your Change Implementation and Management Plan should include the following:
An executive summary of the issues that are currently affecting your organization/workplace (This can include the work you completed in your Workplace Environment Assessment previously submitted, if relevant.)
A description of the change being proposed
Justifications for the change, including why addressing it will have a positive impact on your organization/workplace
Details about the type and scope of the proposed change
Identification of the stakeholders impacted by the change
Identification of a change management team (by title/role)
A plan for communicating the change you propose
A description of risk mitigation plans you would recommend to address the risks anticipated by the change you propose
