at least 250 words and 2 scholarly reference within last 5 years
Choose a medical condition from the gastrointestinal or genitourinary systems and explain the pathophysiology changes that may occur. What patient education would need to be included related to this disorder? Choose a medical condition different from that of your fellow students.
1) Explain the importance of training and development.
2) Discuss how training needs are identified.
3) Analyze Harrods method of developing its employees. Consider the strengths and
weaknesses of such a program.
4) Evaluate the benefits for Harrods in providing a training program. To what
extent do you think the training has achieved a Return on Investment?
reply to classmate’s post , at least 150 words and 1 scholarly reference within last 5 years
Patients with peripheral arterial disease (PAD) typically demonstrate multivessel disease and may also exhibit coronary artery disease. Individuals with PAD, whether symptomatic or asymptomatic are at an increased risk for cardiovascular mortality. Antiplatelet therapy along with risk factor reduction is the hallmark treatment to reduce cardiovascular events in patients with PAD (Patti, Micieli, Cimminiello, & Bolognese, 2020). Clopidogrel, also known as Plavix, is approved for the prevention of atherosclerotic events associated with PAD (Whalen, 2018).
Clopidogrel is a prodrug, which is absorbed in the intestine and activated in the liver. 85% of the drug is hydrolyzed by esterases into an inactive compound, leaving only 15% available for hepatic metabolism. CYP 2C19 participates in oxidative steps to convert clopidogrel into its active metabolite (Wang et al., 2015). Clopidogrel inhibits the binding of ADP to the P2Y12 receptor on platelets, blocking their ability to bind to fibrinogen and to each other, irreversibly. Maximum inhibition of platelet aggregates is achieved in 3-5 days. For quicker effect, oral loading doses may be required. Due to metabolism by CYP 2C19, genetic polymorphism can lead to a decreased clinical response in patients who are poor metabolizers. Tests are available to identify poor metabolizers, as other antiplatelet drugs would be more appropriate in this case (Whalen, 2018). Drugs that inhibit CYP 2C19, such as omeprazole and esomeprazole should be avoided as they can decrease the anti-thrombotic effect of clopidogrel. However, it is important to note that other proton pump inhibitors like, pantoprazole or raberprazole do not affect the pharmacokinetics of clopidogrel (Wang et al., 2015). Furthermore, there is an increase risk of bleeding when clopidogrel is taken with NSAIDs, warfarin, SSRIs and SNRIs (Carter, & Felicilda Reynaldo, 2020).
The most serious adverse effect of using clopidogrel is prolonged bleeding, for which there is no antidote (Whalen, 2018). Other adverse reactions include, epistaxis, hematuria, bruising, rash, hypersensitivity, thrombotic thrombocytopenic purpura (TTP), acute liver failure, angioedema and agranulocytosis. Common side effects include pruritis, purpura, diarrhea and rash (Carter, & Felicilda Reynaldo, 2020). Although there is no lab monitoring that is required for clopidogrel, unlike warfarin, nurses should report signs of TTP, hemolytic anemia, neurologic changes, renal dysfunction and fever immediately.
Please describe what you think would be the ideal role and structure of a central bank for the United States? Would you make changes from the current structure? If so, how? Why? If not, why not?
What are the Federal Reserves policy goals or its targets? Do you believe the Federal Reserve has the tools necessary to accomplish its current set of policy goals? Would you suggest changes to the Feds existing set of goals? What should they be? Why? If not, why not?
Are there any regulatory rules or practices you would alter? Why?
How do the policies of the Harding, Coolidge and Hoover administrations contribute to the Great Depression? How deep was the prosperity of the Roaring 20s? What were the effects of Prohibition on society? Why does Hoover fail to act to protect people? What are the consequences of routing the Bonus Marchers?
Identify any good or service in which you are familiar
List and describe any two to three factors that influence the demand for the good. Explain how it will increase or decrease demand.
List any one or two factors that impact supply for the good. Explain how it will increase or decrease supply.
Finalization of title and research questions.
After going through the past literature, you will develop a clear idea of the gap in the area of your selected topic.
Explore this gap and find a suitable title for your chosen research topic.
Please note that you are naming your research, earlier it was just broad topic.
Draft research questions can be tweaked or improved with the gained knowledge from literature review.
The title and the research questions can be finalized with strong logic provided by supportive literature.
At this stage, you are expected to finalize the title and the research objectives.
*** Support your submission with course material concepts, principles, and theories from the textbook along with the scholarly, peer-reviewed journal articles.
***APA style guidelines, citing references as appropriate.
Submit your findings in a 4 page document, excluding the title page, abstract and required reference page, which are never a part of the requirements
and you need to include the reference listing with a hyperlink to the article.
*Please write a brief theological reflection on the particular pastoral care issue you identified in “Reflection Paper 1”.
*Focus on the following questions:
– What particular spiritual/theological questions are raised by the situation?
– What biblical foundations/themes/Scriptures can you use to build your response to that situation?
This is an argumentative essay for my college history class. We use the “Give me Liberty” An American History Brief Volume 2 by Eric Foner. The following are the exact instructions from the teacher:
You are to write an essay of no more than one single spaced page. You must use standard margins and cite all sources using either MLA or APA, your bibliography may be on the second page. Failure to cite your sources can result in an F for the assignment. The link for submitting your essay is inside this folder.
Remember: You are being graded not on the position you take, but on your ability to make a reasoned, supported, and well written argument
Answer the following questions (Cite your textbook/articles to support ideas): Article is attached. Textbook is : Introduction to Research and Medical Literature for Health Professionals by Forister and Blessing. 5th edition. https://books.google.com/books/about/Introduction_to_Research_and_Medical_Lit.html?id=B9KVBgAAQBAJ
Do you feel the authors provided enough detail in their literature review about the problem they are investigating? If so, what makes you think this, and if not, what could they have provided to clarify their ideas?
Review the Methods section
Do you feel the sample was large enough and could they have chosen their sample differently, if so how?
Is the data reliable and valid? Explain your answer
Review the findings/results- do you agree with them? Is there anything you would have also liked to have been collected and why?
Compare this information to that supplied in the Otiz article that you read in week 1. Which article do you feel supplies you with a stronger literature review ? Which one discussed the methods better and why?
Cite at least one source to support your ideas using APA in-text citation. Posting should be at least a paragraph or more in length with well developed ideas.
Writing reflects understanding of concept(s) in the assigned readings. Applies textbook and other sources. Includes personal viewpoints to support answer.
Uses references as appropriate.
